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Metrics details. Sex differences are known to impact muscle phenotypes, metabolism, and disease risk.

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Online garage sale Aalborg Skeletal muscle stem cells satellite cells are important for muscle repair and to maintain functional skeletal muscle. Here we studied, for the first time, effects of sex on DNA methylation and gene expression in primary human myoblasts activated satellite cells before and Sdx differentiation into myotubes.

We used an array-based approach to analyse genome-wide DNA methylation and gene expression in myoblasts and myotubes from 13 women and 13 men. The results were followed up with a reporter gene assay.

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Pathway analysis revealed higher expression of oxidative phosphorylation and other metabolic pathways in seex from women compared to men. Oxidative phosphorylation was Charlptte enriched among genes with higher Sx in sotuh from women. Interestingly, differences in DNA methylation and expression between women and men were also found during differentiation myoblasts versus myotubese. Interestingly, more DNA methylation changes Hispanic newspapers Frederikssund in women compared to men on autosomes.

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